Peptide Processor Rates by Volume Tier

Full fee schedule for RUO peptide payment processing. Graduated pricing, rates drop automatically as monthly volume grows.

By Blake Toves, Founder at Holistic Payments · Published April 17, 2026

Peptide processing rates start at 9.5% for $30K–$80K/mo and scale down to 6.5% at $500K–$1M/mo. Above $1M/mo, rates are negotiable. No setup fees, no monthly minimums, no account fees, you pay only the per-transaction processing rate. Graduated pricing: as your volume grows, you automatically move to the next tier's lower rate.

Full rate schedule

Monthly volumeRateEffective blend*
$30K – $80K9.5%~9.8% with Shopify 3P fee
$80K – $150K8.5%~8.7% with Shopify 3P fee
$150K – $250K7.5%~7.6% with Shopify 3P fee
$250K – $500K7%7%–7.15%
$500K – $1M6.5%6.65% with Shopify 3P fee
$1M+Negotiable6% and below, deal-dependent

*"Effective blend" shows the all-in rate including Shopify's third-party gateway fee (0.15%–2% depending on plan) for Shopify merchants. WooCommerce and direct API merchants pay only the headline rate.

What's included in the rate

No extra charges

Pass-through at cost

Graduated pricing: how volume triggers rate drops

Your rate automatically moves to the next tier's rate once you cross the volume threshold for three consecutive months. No renegotiation needed. For example, a merchant starting at the $30K–$80K (9.5%) tier who hits $85K, $95K, $102K in three consecutive months is moved to the 8.5% tier for the following month.

This matters for scaling brands: the difference between 9.5% and 6.5% on $500K/mo is $15,000/mo. Graduated pricing means you capture that savings automatically.

Comparison: U.S. bank vs. offshore/high-risk specialists

U.S. Bank (Holistic)Offshore / High-Risk Specialist
Headline rate6.5%–9.5%3%–5% (quoted)
SettlementDaily, 48 hrWeekly, T+7 to T+14
Reserve10%/90d or 15%/60d, released to 0%20%+ rolling, often not released
CurrencyUSDUSD or multi-currency with FX spread
Approval1–2 weeks2–6 weeks
MATCH exposureLow, U.S. bank acquirerHigher, some use secondary MIDs
Authorization rate~90%70–85%

Offshore rates look lower on paper but the effective cost, after accounting for reserve holds, longer settlements, FX spreads, and lower authorization, often exceeds the U.S. bank rate. A 4% offshore rate with a 20% rolling reserve and 14-day settlement loses more on float and auth decline than a 7.5% U.S. bank rate breaks even.

FAQ

Can I get a promotional rate for the first few months?

No promos, no teaser rates. The schedule is straightforward, you get the rate for your tier from day one.

What if I process both peptides and non-peptide merch (apparel, swag)?

Peptide-volume tier determines the rate across both. If your total volume is $100K/mo ($60K peptides + $40K merch), you land in the $80K–$150K tier at 8.5% for all transactions.

Do rates include American Express?

Yes. The headline rate applies to Visa, MasterCard, Discover, and American Express. Amex transactions sometimes carry a slightly higher interchange but it's absorbed into the blended rate you see.

What's the per-transaction authorization fee?

$0.25 per authorization, on top of the percentage rate. For a $100 transaction at 8.5%, total cost = $8.50 + $0.25 = $8.75. For a $1,000 transaction at the same rate, total = $85 + $0.25 = $85.25.

Ready for U.S. bank peptide processing?

Complete the intake form. Approval typically in 1–2 weeks.